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Summary of Transcript:
A recent study found that just 30 days of Ramadan fasting, which involves fasting for 17 to 19 hours per day, led to significant improvements in levels of autophagy and an increase in a tumor suppressor protein known as p53. This supports longevity, metabolic health, and aging. The study also found changes in cellular senescence, which is when cells become senescent and release inflammatory biomarkers. The study looked at different inflammasome and autophagy related biomarkers, and found favorable changes within the inflammasome Hub and a decrease in senescence Associated signaling molecules over time. The study recommends further studies to understand how intermittent fasting influences these genes and every gene affects every other to see how it affects overall lifespan and disease incidence in different people. Consistent intermittent fasting for just 17 hours a day is achievable and leads to a more than two-fold expression in autophagy initiation proteins and the autophagy inhibitor protein.
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Summary of Description:
A study has found that fasting for 17 to 19 hours a day for 30 days increases autophagy, decreases senescence-associated signaling molecules and increases tumor suppressor P53, which helps repair DNA damage and reduces atherogenic risk. However, long-duration fasts may catabolize lean mass, increasing the risk of cardiovascular disease. The benefits of autophagy are tissue-specific, particularly in the liver and brain. Regular exercisers also have a higher increase in autophagy initiation proteins during fasting.
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Ideal Fasting Time for Supporting Longevity and Aging
Fasting has been a subject of research for a long time, and its ability to enhance longevity and decelerate aging has been the subject of numerous studies. A recent study, however, narrows down the ideal fasting time required to achieve these benefits.
Fasting for 17 to 19 Hours Promotes Autophagy and Tumor Suppressor P53
Researchers enrolled participants in a 30-day fasting program to observe its effects on the body. The participants fasted for 17 to 19 hours every day for 30 days, and the researchers studied the effects of their fasting on the body.
The results of the study showed that 17 to 19 hours of fasting per day significantly increased autophagy, which is the body’s process of cleaning up damaged cells, and increased the tumor suppressor P53. Autophagy is a key factor in maintaining cell health and longevity, and P53 helps in repairing DNA damage, preventing senescence, and contributing to reduced atherogenic risk.
Autophagy, Inflammasome Hub and Senescence-Associated-Signaling Molecules
Not only did the study show an increase in autophagy, but also, it revealed favorable changes in the inflammasome hub and a decrease in senescence-associated-signaling molecules. This points towards a decrease in inflammation and aging, which are major contributors to chronic illnesses.
Tissue-Specific Benefits of Autophagy
The study also revealed the tissue-specific benefits of autophagy, particularly in the liver and brain. These organs are vital for maintaining overall health and are affected by aging, making the benefits of autophagy even more important.
Exercise and Autophagy
Apart from fasting, exercise is another way to induce autophagy. Regular exercisers have a greater increase in fasted-associated autophagy initiation proteins, making the combination of exercise and intermittent fasting an effective way to promote autophagy and maintain overall health.
Long Term Fasting and Cardiovascular Health
While long-term fasting has many health benefits, there is a downside to it. Long duration fasts can catabolize lean mass, possibly increasing the risk for cardiovascular disease. Therefore, it is important to balance the benefits of fasting with the potential negative effects and consult a healthcare provider before starting on any fasting regimen.
Berberine Fasting Accelerator by MYOXCIENCE
For those looking to support their intermittent fasting lifestyle, the Berberine Fasting Accelerator by MYOXCIENCE is a great supplement to add. It supports stable blood sugar levels, peak AMPK activation and reduces inflammation, making it an ideal supplement for fasting and maintaining overall health.
Conclusion
Fasting is an effective tool for promoting longevity and decelerating aging. The ideal fasting time to promote autophagy and other health benefits is 17 to 19 hours per day, as revealed by the recent study. However, it is important to consult healthcare professionals and balance the benefits of fasting with the potential negative effects to maintain overall health. Adding supplements like the Berberine Fasting Accelerator by MYOXCIENCE can also support the intermittent fasting lifestyle and promote overall health.
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Source Description
A new study discusses the ideal fasting time for supporting longevity, aging.
Support your Intermittent Fasting lifestyle with the Berberine Fasting Accelerator by MYOXCIENCE: https://bit.ly/berberine-fasting-accelerator
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Link to research and detailed show notes: https://bit.ly/Erythritol-study-breakdown
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0:00 Intro
0:00 Fasting 17 to 19 hours per day for 30 days increased autophagy and increased tumor suppressor P53.
2:10 Autophagy increased, favorable changes were made in the inflammasome hub, and there was a decrease in senescence-associated-signaling molecules.
3:00 P53 helps repair DNA damage, prevents senescence, and contributes to reduced atherogenic risk.
6:05 Autophagy has tissue-specific benefits, especially in the liver and brain.
7:35 Regular exercisers have a great increase in fasted-associated autophagy initiation proteins.
8:35 Long duration fasts can catabolize lean mass, possibly increasing risk for cardiovascular disease.
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