Gut Microbiome: Vital Role explained (Part #1)

Gut Microbiome: Vital Role explained (Part #1)

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Summary of Transcript:
The gut microbiome refers to all microorganisms in a person’s gastrointestinal tract, including bacteria, fungi, parasites, and their gene content. The gene content of the microbiome is three times that of the human genome and produces bioactive components that affect numerous aspects of human health. Non-fermentable fibers promote motility, while microbial accessible fibers facilitate fermentation and metabolite production. The gut microbiome is just one of several microbiomes in the human body and is related to other microbiomes found in moist mucosal surfaces. Diet and exercise research is having a “renaissance,” and more nutrition researchers in microbiome research are needed. Despite the amount of research done, we still know only a fraction of what we need to know about the gut microbiome in relation to health and disease.

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Summary of Description:
Dr. Suzanne Devkota, Director of the Human Microbiome Research Institute at Cedars-Sinai Medical Center, discusses her research on the gut microbiome and its effects on inflammatory diseases and metabolic diseases. In an episode of The Dr. Gabrielle Lyon Show Podcast, she talks about topics including the failure of fasting and other diets, the necessity of fiber in diets, the dangers of leaky gut, and the negative impact of food additives. Dr. Devkota emphasizes the importance of studying microbiomes to achieve better health outcomes and encourages people to seek medical advice before making changes to their diet. The episode also features several sponsored promotions.


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The Importance of Gut Health: A Conversation with Dr. Suzanne Devkota

Dr. Gabrielle Lyon, a renowned functional medicine physician, recently sat down with Dr. Suzanne Devkota, Director of the Human Microbiome Research Institute at Cedars-Sinai Medical Center, to discuss the impact of diet on gut health and inflammation. Here are the highlights of their conversation, from the importance of fiber to the dangers of leaky gut.

Why Fasting and Other Diets Don’t Work

Many people turn to fasting, keto, or other diets as a way to improve their gut health, but Devkota argues that these diets are often too extreme and not sustainable. Instead, she recommends a balanced and varied diet that includes plenty of vegetables, fruits, and whole grains.

Do You Really Need Fiber in Your Diet?

Devkota stresses the importance of fiber in the diet, particularly for the health of the gut microbiome. Fiber acts as a prebiotic, feeding the good bacteria in the gut and promoting their growth. In addition, fiber helps to regulate digestion and prevent constipation.

Why You Should Be Worried About Leaky Gut

Leaky gut is a condition in which the lining of the intestine becomes damaged, allowing undigested food particles and toxins to leak into the bloodstream. This can trigger inflammation and contribute to a range of health problems, including autoimmune diseases and allergies. Devkota recommends avoiding processed foods and taking steps to reduce stress, both of which can contribute to leaky gut.

Are Food Additives Bad for You?

Many food additives, such as preservatives and artificial sweeteners, have been linked to negative health effects. Devkota recommends avoiding processed foods and opting for fresh, whole foods whenever possible.

Testing Your Gut Microbiota

One of the key areas of research in Devkota’s lab is the relationship between the gut microbiome and metabolic diseases such as diabetes and obesity. She notes that there is still a lot to learn about this relationship, but testing for specific strains of bacteria can provide important information about an individual’s gut health.

The Bottom Line

Overall, Devkota emphasizes the importance of a balanced and varied diet, as well as lifestyle factors such as exercise and stress reduction, in promoting gut health. While there is still much to learn about the gut microbiome and its impact on human health, this is an exciting area of research that holds promise for the development of new treatments and preventive measures.

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Source Description
Dr. Devkota is Director of the Human Microbiome Research Institute at Cedars-Sinai Medical Center in LA and an Associate Professor of Medicine at UCLA, as well as an adjunct investigator at the Joslin Diabetes Center at Harvard Medical School. She has been studying the effect of diet on the gut microbiome and inflammatory diseases for the past 12 years. investigating dietary drivers of gut microbiome structure and function in inflammatory bowel diseases and metabolic diseases. Her research has been published in top journals Nature, Science, and Cell, and is funded by the National Institutes of Health. She completed her masters at the University of Illinois at Urbana-Champaign in Nutritional Sciences, her Ph.D in Molecular Metabolism and Nutrition at The University of Chicago, and her post-doctoral training at the Joslin Diabetes Center at Harvard Medical School.

In this episode we discuss:
• Why fasting and other diets don’t work
• Do you really need fiber in your diet?
• Why you should be worried about leaky gut
• Are food additives bad for you?

This episode is brought to you by One Farm, LMNT, 1stPhorm, Inside Tracker

Devkota Lab Website: https://www.devkotalab.com/
Suzanne’s IG: https://www.instagram.com/suzannedevkota/

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Timestamps
00:00 Coming up on The Dr. Gabrielle Lyon Show
01:15 One Farm
02:55 Introducing Suzanna Devkota
05:12 The need for nutritional scientists in the microbiome space
06:32 What is the gut microbiome?
08:44 Is the microbiome only related to the gut?
10:10 What studies are done in Suzanne’s lab
12:37 Obesity and bacteria
14:25 Nutritional aspects of gut health & leaky gut
19:52 How do you know if you have a leaky gut?
23:36 LMNT Electrolytes
25:06 Do we know if artificial sweeteners affect the gut microbiome?
28:24 Foods to avoid for gut health
29:45 Food additives
31:26 Top three things that wreck your gut microbiome
34:32 Fermented foods and fiber
45:53 Traveling and your guts circadian rhythm
49:45 1st phorm
51:15 Can the people you live with influence your microbiome?
53:31 Fecal transplants
1:00:00 Testing your gut microbiota
1:05:06 InsideTracker

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