Microbiome Communication with Cells | Theresa Alenghat

Microbiome Communication with Cells | Theresa Alenghat

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Summary of Transcript:
Our bodies are home to trillions of microorganisms known as the microbiome, which can be beneficial for digestion, boosting immunity, and preventing conditions such as obesity, allergy, and asthma. Differences in the microbiome can fluctuate due to diet, stress, or medicine, and diseases such as diabetes, inflammatory bowel disease, autism, and cancer have been linked to changes in the microbiome. Research is investigating how microorganisms communicate with our bodies and the impact of our diet on the microbiome. The study aims to develop strategies to modify diet or use products made by bacteria to harness the power of our microbiome to promote health and treat disease.

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Summary of Description:
Theresa Alenghat is a scientist researching the relationship between our gut microbiome and health. Her research has revealed new pathways for how our microbiome impacts infection, obesity, and inflammation. She shares how bacteria in our gut communicate with our cells and how diet can affect this relationship. This research opens doors to new ways to improve health by harnessing the power of the microbiome. Theresa has received multiple prestigious awards for her research and strives to break down barriers for women in science.

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Exploring the Relationship between the Microbiome and Our Health

The microbiome comprises all the microorganisms in our gut, including bacteria, viruses, fungi, and other organisms. Our gut is home to trillions of harmonious microbes, creating a complex ecosystem where they interact with our bodies in ways we are continually discovering. In a TEDx presentation, scientist Theresa Alenghat, who runs a research lab at the Immunology Division of Cincinnati Children’s Hospital, shares how her research has revealed new pathways for how our microbiome impacts infection, obesity, and inflammation.

The Importance of the Microbiome

The microbiome plays a crucial role in shaping our health and well-being, influencing everything from our immune system, digestion, brain function, and mental health. Over the last two decades, research has shown us that the microbiome is essential for our overall health, with a growing understanding of how gut bacteria help maintain intestinal health, reinforce the gut barrier, and protect us from harmful microbes.

Bacteria Communication with Our Cells

Theresa Alenghat’s research has been illuminating, showcasing how bacteria in our gut communicate with our cells, influencing various physiological processes. This relationship between our cells and bacteria in our hearts is vital to maintaining a healthy microbiome. Alenghat explains that the communication between these two entities is a conversation, with the gut microbiome talking to our immune cells. It is essential to note that humans play an active role in shaping the communication between these two entities through food consumption.

The Role of Diet in Shaping Our Microbiome

The food we eat has a profound impact on our microbiome, and this is because food influences the composition and function of the microbiome. Alenghat posits that diets high in fat and sugar can significantly alter the behavior of bacteria in our gut, impacting our metabolic health. This means that individuals should watch their diet, ensuring they consume more fiber-rich foods while limiting the high consumption of highly processed and sugary foods.

The Impact of the Microbiome on Obesity

Alenghat’s research has also revealed that obesogenic diets, that is, diets high in sugar or fat, can drive conditions such as obesity by impacting the gut microbiome. The microbiome has been shown to play a critical role in preventing weight gain, as it regulates energy balance, but the catch is it depends on the kind of bacteria in our gut. Studies have shown that individuals with a lower diversity of certain types of bacteria and a diet-high fat are more likely to gain weight or become obese.

The Future

Looking ahead, Theresa Andelghat’s research provides a window into how our microbiome impacts our health in ways we don’t fully understand. It is essential to note that we are still in the early stages of unlocking the secrets of the microbiome, and there is much to learn; however, what is clear is that the microbiome is an essential piece of the puzzle in maintaining optimal health. Harnessing the power of the microbiome could help establish new treatments for various conditions, including obesity, diabetes, and other inflammatory diseases.

In conclusion, Theresa Andelghat’s research has highlighted new pathways for understanding our relationship with bacteria that live in our gut. Our gut microbiome plays an essential role in maintaining our health, and it is up to each individual to ensure they are making choices that promote good gut health. Additionally, harnessing the power of the microbiome could help establish new treatments for various conditions as we continue to unlock the secrets of the microbiome.

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Source Description
Scientist Theresa Alenghat runs a research lab investigating our relationship with microorganisms that usually live in our gut (our microbiome). Her research has revealed new pathways for how our microbiome impact infection, obesity, and inflammation. Theresa shares how bacteria in our gut communicate with our cells and how diet can affect this relationship. This type of research illustrates that our bodies are quite sensitive to an ongoing dialogue with microorganisms in our gut and opens doors to a new range of ways to improve health by harnessing the power of the microbiome. Theresa has received multiple prestigious awards for her research. She is also a mom who strives to break down barriers for women in science. Follow on Twitter @AlenghatLab. Theresa Alenghat is a faculty member in the Immunology Division of Cincinnati Children’s Hospital. She runs a research lab investigating our relationship with bacteria that usually live in our intestines. Her research has revealed new pathways for how our microbiome impacts infection, obesity, and inflammation. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx.

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