The Science of Longevity: Understanding Fasting, mTOR, and Autophagy
You’re walking down a well-worn path you’ve traversed so often you’ve lost count. Imagine you could find a detour, a shortcut to a healthier, more vibrant existence. This detour isn’t paved with high-tech gadgets, grueling workout regimens, or expensive elixirs. Instead, it’s paved with…well, a lot of nothing.
Yes, you heard it right—nothing. We’re talking about fasting, a time-honored tradition of bodily abstinence from food. But this isn’t your grandmother’s fasting. The emerging science of longevity paints a fascinating picture of what fasting, done just right, can mean for our health. And we’re not just talking about weight loss. As it turns out, fasting is a powerful tool in managing our body’s growth pathways, fostering resilience, and promoting vitality.
Meet mTOR: Your Body’s Growth Maestro.
First, let’s get acquainted with a real bigwig in human biology—a protein complex called mTOR, or the mammalian target of rapamycin. mTOR is like a grand maestro orchestrating your body’s symphony of growth and development. It takes center stage when it’s time for your cells to divide, grow, and synthesize proteins. But what happens when the conductor doesn’t know when to drop the baton?
Too much mTOR activation—akin to that maestro waving his baton relentlessly—can lead to many problems. From aging to metabolic disorders, the list goes on. The constant stimulation of growth and replication can cause our cells to lose touch, leading to a deterioration of health over time.
The Fasting Solution: Embracing Quietude and Repair
Enter fasting. Fasting can work wonders, like a beautifully timed intermission in the middle of a concert. This break halts our cells, allowing for a unique process called autophagy. During autophagy, our cells become janitors, meticulously cleaning up and recycling damaged parts, rejuvenating themselves. A fantastic housekeeping strategy that contributes to our cellular architecture’s stability and longevity.
How does one fast for this longevity magic? Tactfully alternating between longer fasts (18-22 hours) a few days a week and shorter modified fasts (14-16 hours) on the other days. Now, this isn’t a hunger game. It’s about learning to eat right within the feeding windows. For instance, consider packing in a bit more protein during the longer fasts.
Be Mindful of Your Gut Health
And remember, fasting isn’t a free pass to neglect your gut health. Your gut is an intricate ecosystem of diverse microbes, and these tiny tenants need your love and attention. A well-nourished gut microbiome can make a difference in nutrient absorption, inflammation levels, and mood regulation. So, don’t forget to pamper your gut with fiber-rich, whole foods during your eating windows.
Fasting and Longevity: A Symphony, Not a Solo
Finally, it’s essential to remember that, although powerful, fasting is not a magic bullet for longevity. It’s one instrument in the orchestra of a healthy lifestyle. Other critical players in this symphony are regular exercise, stress management, quality sleep, and maintaining social connections.
So, are you ready to take the detour, to march to the beat of a different drum? Remember, every journey starts with a single step—or in this case, maybe a skipped meal. In the grand concert of life, fasting might be the best note you need to keep the music playing beautifully for a long, long time.
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Summary of Transcript:
The video discusses how to fast for longevity, emphasizing caloric and protein restriction. The main focus is on the mammalian target of rapamycin (mTOR), a growth switch that stimulates growth but can also degrade health over time. Fasting allows for periods of consolidation and autophagy, where the body repairs and rejuvenates itself. The video recommends doing longer fasts (18-22 hours) a couple of days per week, with higher protein intake during those periods, and shorter modified fasts (14-16 hours) on the other days. It’s essealso vital to be mindful of gut health during fasting periods. The video concludes by emphasizing that while fasting can help with longevity, it’s not guaranteed and should be done with overall healthy lifestyle choices.
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Summary of Description:
The video discusses how to fast for longevity and provides a complete guide. The video includes a paid partnership with a brand that supports the channel and offers a 30% discount code for the brand’s products. The video covers the benefits of fasting, including its effects on mTOR and protein restriction, and offers advice on what to do on non-fasting days. The video concludes by providing a fasting plan.
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Source Description
Use Code THOMAS30 for 30% off Your First Order from SEED: https://www.seed.com/thomasyt
How to Do Fasting for Longevity – Complete Guide
This video does contain a paid partnership with a brand that helps to support this channel. Because of brands like this, we can provide the content we do for free.
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References
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798000/pdf/ukmss-28028.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884086/pdf/glq042.pdf
https://pubmed.ncbi.nlm.nih.gov/8429371/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562018/pdf/main.pdf
https://pubmed.ncbi.nlm.nih.gov/16574059/
Timestamps ⏱
0:00 – Intro – How to Do Fasting for Longevity – Complete Guide
0:57 – Fasting, Longevity & mTOR
4:20 – Protein Restriction & Benefits of Muscle
5:45 – Here’s What to Do
7:55 – Use Code THOMAS30 for 30% off Your First Order from SEED!
8:29 – What to do on Non-Fasting Days
13:17 – The Plan
