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Summary of Transcript:
David Sinclair is a guest on a podcast and believes this will be one of the essential podcasts he ever does. He starts by telling a story of a poker dealer who died of a heart attack at 40 and questions how we can genuinely determine our biological age. He then quotes himself from a previous podcast, saying that aging is controllable. We have the technology to slow or reverse it, fundamentally changing human history. Sinclair explains that he believes aging is a loss of information in the epigenome, a layer of genetic information that reads the DNA. He also talks about how enzymes pick up the building blocks of DNA and proteins to build chains and how humanity is building machines to store all the world’s information in a biological test tube.
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Summary of Description:
The latest Impact Theory podcast episode focuses on longevity and how we can slow down or even reverse the aging process. Tom Bilyeu is joined by Dr. David Sinclair, a genetics expert, to talk about the science of aging and what it’s possible to do to extend our lives. Dr. Sinclair explains that we have the technology to reverse aging, citing examples such as the reversal of eye aging, and discusses the importance of facing adversity to maintain a healthy and youthful body. The podcast is recommended for anyone interested in improving their quality of life as they age.
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Can We Reverse Aging? Dr. David Sinclair Explains
Is it possible for humans to become biologically immortal? This may seem like a far-fetched idea, but Dr. David Sinclair, a leading geneticist, believes it may be within reach. In a recent episode of Impact Theory, Dr. Sinclair discusses why we age on a cellular level and what can be done to slow down and even reverse our biological clock.
Why We Age
Dr. Sinclair explains that our cells accumulate damage over time, causing them to lose function and ultimately die. Genetic and environmental factors, such as exposure to toxins and poor lifestyle habits, influence this aging process.
What Goes Wrong With Aging
As we age, our cells become less efficient at repairing themselves and removing waste. This leads to a buildup of damage and inflammation, which can cause chronic diseases such as cancer, Alzheimer’s, and heart disease.
How to Reverse Aging
Dr. Sinclair and his team of researchers are working on several strategies to reverse aging, including activating the body’s natural repair mechanisms and using gene therapy to restore damaged cells. One promising approach is reprograming cells to a more youthful state, turning them into stem cells that can regenerate tissues.
Face Adversity
Interestingly, Dr. Sinclair notes that our bodies respond well to perceived adversity. By exposing ourselves to mild stressors such as exercise, fasting, and exposure to extreme temperatures, we can stimulate our bodies’ natural repair mechanisms and stay healthy for longer.
Metformin and Lifestyle for Longevity
Dr. Sinclair also discusses the potential anti-aging benefits of metformin, a diabetes drug that has been shown to extend the Lifespan of animals. He also emphasizes the importance of a healthy lifestyle, including regular exercise, a balanced diet, and adequate sleep.
Overall, Dr. Sinclair’s research offers exciting possibilities for extending the human Lifespan and improving the quality of life in our later years. Who knows, maybe one day we’ll all be living to 150! o learn more about his work, check out his newest podcast, Lifespan, or follow him on social media.
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Source Description
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Are we closer to becoming biologically immortal? What would you strive to do or dream of if you could extend your life to even 150 years? Until recently, the idea of longevity felt more like reaching your 90s and possibly 100 at best, and if you manage to accomplish that goal, high quality of life would be best and expected. But what if you could extend your Lifespan by even 10 years? Making sure that those years are exciting and meaningful would be a priority. Dr.David Sinclair, a world-renowned geneticist, is joining Tom in this episode to break down exactly why we age on a cellular level and what is now becoming possible in terms of slowing down our biological clock and even possibly reversing our biological age. If you want to know what you can do to start improving the quality of your aging life and stay younger longer, t, this is for you, and you’ll want to check out Dr. David Sinclair’s newest podcast, Lifespan (link below).
SHOW NOTES:
0:00 | Introduction to David Sinclair
0:28 | Why We Age
9:40 | What Goes Wrong With Aging
23:44 | How to Reverse Aging
37:35 | Face Adversity
45:37 | How Metformin Works
55:02 | Lifestyle for Longevity
“We could have reversed aging just by making all cells stem cells; we have the technology to do that.” [23:43]
“So we’re reversing the eye’s aging, that’s not hard at all, but we can reverse the age of the liver, the skin, other labs are doing the spleen, thymus, through this method.” [31:13]
“Humanity lucked out that we can do this and that there’s a backup copy of youth in each of our cells that can be tapped into.” [32:03]
“We don’t think about what it’s like at the end; it is not fun. It’s not typically like, Oh, you go to sleep. Those are the lucky ones.” [36:39]
“The main concept that I think we all need to remember is that our bodies respond well to perceived adversity.” [38:55]
Follow David Sinclair:
Website: https://sinclair.hms.harvard.edu/
YouTube: https://www.youtube.com/davidsinclairpodcast
Podcast: https://anchor.fm/lifespan
Instagram: https://www.instagram.com/davidsinclairphd/
Twitter: https://twitter.com/davidasinclair
Facebook: https://www.facebook.com/davidsinclairphd
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