Summary of Lifestyle Program Reverses Biological Age:
A study published in Aging found that an 8-week methylation-supportive diet and lifestyle program can decrease biological age in women. The program, which involved guidance on diet, sleep, exercise, relaxation, supplemental probiotics and phytonutrients, and nutritional coaching, decreased biological age by an average of 4.60 years in a case series of six women. The study expands on a previous pilot study that found similar results in men. The researchers suggest that such interventions may affect underlying mechanisms of aging rather than disease-driven Aging and may be effective for both sexes.
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Aging and Biological Age: Can Methylation-Supportive Diet and Lifestyle Program Aid Reversing Biological Age?
Introduction: Understanding Biological Age and Aging
Biological age, also known as physiological age, measures how quickly our body is aging. This measurement is distinct from chronological age, measured by how many years we have lived. Biological age is determined by analyzing changes in our DNA caused by environmental factors like diet, stress, and exercise. As we age, our bodies undergo various changes that can lead to multiple age-related diseases.
Research Study: Methylation-Supportive Diet and Lifestyle Program
A new study published in Aging investigates the impact of a methylation-supportive diet and lifestyle program on biological age. The study focuses on a case series of six women who underwent an eight-week program that included guidance on diet, sleep, exercise, relaxation, supplemental probiotics, and phytonutrients – all aimed at affecting DNA methylation and measures of biological Aging. The research team then analyzed DNA methylation and biological age on blood samples at baseline and the end of the eight weeks.
Results: Biological Age Reduction Following Methylation-Supportive Diet and Lifestyle Program
Five of the six participants exhibited a biological age reduction of between 1.22 and 11.01 years from their baseline biological age. There was a statistically significant difference in the participants’ mean biological age before (55.83 years) and after (51.23 years) the eight-week diet and lifestyle intervention, with an average decrease of 4.60 years. The average chronological age at the program’s start was 57.9 years. Still, one participant had a biological generation younger than their chronological age at the beginning of the program, suggesting that physical age changes were unrelated to disease improvement and might be attributed to underlying aging mechanisms.
Conclusion: Methylation-Supportive Diet and Lifestyle Programs’ Effectiveness in Reversing Biological Age
The study’s results suggest that a methylation-supportive diet and lifestyle intervention can favorably influence biological age in both sexes during middle age and older. The program used in the study was first investigated in a pilot clinical trial in which participants reduced their biological age by an average of 3.23 years compared to controls. The case series reported herein was conducted to further the investigation of a modifiable lifestyle intervention that was largely the same in other populations, especially in women. The findings suggest that such interventions may affect underlying mechanisms of aging rather than disease-driven Aging and may be effective for both sexes.
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