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Summary of Transcript:
This podcast discusses the effects of menopause on cardiovascular risk, specifically the loss of estradiol, which leads to an increase in LDL. This is due to a decrease in estrogen levels during perimenopause, which can last several years before menopause. After menopause, women have lower levels of estrogen than men do, and even pre-menopause women have higher testosterone than estrogen. There are also changes to estrone E1, which is the weakest type of estrogen formed in the adrenal glands and other adipose tissues. Post-menopausal women with higher androgen levels and higher testosterone to estrogen ratios have greater risk of developing ASCVD and heart failure. There are also other risk factors such as visceral fat deposition in the abdomen, insulin resistance, dyslipidemia, endothelial dysfunction, and increased sympathetic tone. Estrogen therapy can have both favorable and unfavorable effects, including lowering LDL and increasing HDL, increasing CRP, and being pro-thrombotic. It is not recommended for the sole purpose of cardiovascular disease prevention.
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Summary of Description:
This podcast is from The Peter Attia Drive, a weekly podcast focusing on maximizing health, longevity, critical thinking, and more. It features topics such as fasting, ketosis, Alzheimer’s disease, cancer, mental health, and more. Hosted by Peter Attia, a physician focusing on the applied science of longevity, the podcast is designed to help listeners optimize their health and increase their lifespan. It is available on Apple Podcasts, Overcast, Spotify, and Google Podcasts.
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Cardiovascular Disease in Women: Prevention, Risk Factors, Lipids, and More
Cardiovascular disease is the leading cause of death in women, yet it is often overlooked and underdiagnosed. To help raise awareness and provide valuable insight, Peter Attia, M.D., interviewed Erin Michos, M.D., M.H.S., a cardiologist and epidemiologist who specializes in women’s heart health. In this episode of The Peter Attia Drive podcast, Dr. Michos explains the risk factors for cardiovascular disease in women, the importance of prevention, and the role of lipids in heart health.
Risk Factors for Cardiovascular Disease in Women
Dr. Michos explains that the risk factors for cardiovascular disease in women are similar to those in men, but there are some key differences. For example, women are more likely than men to develop heart disease after menopause, and they are more likely to experience atypical symptoms. Additionally, women are more likely to develop heart disease if they have diabetes, high blood pressure, or a family history of heart disease.
The Importance of Prevention
Dr. Michos emphasizes the importance of prevention in reducing the risk of heart disease in women. She recommends that women maintain a healthy weight, exercise regularly, and eat a balanced diet. Additionally, she recommends that women get regular check-ups and screenings for high cholesterol, high blood pressure, and diabetes.
The Role of Lipids in Heart Health
Dr. Michos explains that lipids—or fats—play an important role in heart health. She recommends that women maintain healthy levels of “good” cholesterol (HDL) and “bad” cholesterol (LDL). Additionally, she recommends that women monitor their triglyceride levels, as high levels of triglycerides can increase the risk of heart disease.
Conclusion
Cardiovascular disease is a leading cause of death in women, but it can be prevented with lifestyle changes and regular check-ups. In this episode of The Peter Attia Drive podcast, Dr. Michos provides valuable insight into the risk factors for cardiovascular disease in women, the importance of prevention, and the role of lipids in heart health. By understanding the risks and taking preventive measures, women can reduce their risk of developing heart disease.
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See Original Source
Source Description
This clip is from podcast # 230 ‒ Cardiovascular disease in women: prevention, risk factors, lipids, and more | Erin Michos, M.D.
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About:
The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 45 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more.
Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life).
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Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user’s own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies.
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