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Summary of Transcript:
In this podcast, Andrew Huberman, a neurobiology and Ophthalmology professor at Stanford School of Medicine, discusses hair from a biological perspective. Hair is fascinating because every individual strand of hair has its own stem cell niche, which gives rise to hair for different periods of time depending on the hair’s location on the body. The podcast covers what regulates stem cells, what allows them to continue producing hair or cease producing hair, how to slow or even halt hair loss entirely, and common myths about hair loss and replacement. Huberman emphasizes that the podcast is separate from his teaching and research roles at Stanford and thanks the podcast’s sponsors: Helix Sleep, hvmn Ketone IQ, and Roca.
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Summary of Description:
The Huberman Lab podcast discusses the biology of hair growth and potential ways to slow or stop hair loss. The episode covers the essential role of hair stem cells and other factors for healthy hair growth, as well as approaches such as minoxidil, tadalafil, PRP, microneedling, Botox, and ketoconazole treatments. The podcast also explains how age-related hormone changes can cause hair loss and explores the effectiveness of treatments such as caffeine, saw palmetto, growth hormone, finasteride, and dutasteride. For each treatment, potential side effects and expected results are discussed. Overall, the podcast provides insight into the science behind hair growth tools and helps listeners evaluate potential treatments.
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The Science of Hair Growth: Understanding the Biology Behind Options for Hair Regrowth
Hair loss, thinning, and baldness are common concerns that can cause anxiety and stress for many individuals. In this episode, Dr. Andrew Huberman of Huberman Lab explains the biology of hair and hair growth, along with the factors that cause hair loss and hair falling out. He discusses the essential role of hair stem cells and other supporting biological factors that contribute to healthy hair growth.
Understanding Hair Anatomy and Stem Cells
To understand hair growth, it is essential to first understand the basic anatomy of the hair shaft and the role of hair stem cells. Dr. Huberman explains that the hair shaft is composed of three layers, with the middle layer containing the pigment-producing cells that give hair its color. He also describes the three phases of hair growth – anagen, catagen, and telogen – and how hair stem cells are essential for ongoing hair growth.
Approaches to Slow Hair Loss
Dr. Huberman outlines various mechanical and chemical approaches to slow hair loss and increase blood flow to hair stem cells. These include treatments such as minoxidil, tadalafil, PRP, microneedling, Botox, and ketoconazole. He also discusses the effectiveness of combination therapies for hair regrowth, even in hair loss “dead zones.”
Age-Related Hormone Changes and Hair Loss
Dr. Huberman also delves into age-related hormone changes and how they can cause hair loss. He outlines the effectiveness of caffeine, saw palmetto, growth hormone, finasteride, and dustasteride in treating hair loss, and provides detailed information on potential side effects, timeline to expect results, and the amount of hair regrowth to expect.
Combination Treatments for Hair Regrowth
Finally, Dr. Huberman highlights effective combination treatments for hair regrowth, and provides comprehensive information on all available treatments, emphasizing their potential side effects, timelines, and amount of hair regrowth to expect.
Evaluation and Selection of Hair Regrowth Treatments
By providing the science behind the options for hair regrowth, Dr. Huberman enables individuals to evaluate potential treatments and select the best one(s) for their specific needs. He emphasizes that thinning, brittle hair, or pattern baldness are not something to be ashamed of, but a common concern that can be addressed with the right treatment plan.
Conclusion
The Huberman Lab believes in empowering individuals with knowledge and understanding, and in this episode, Dr. Huberman provides detailed and comprehensive information on all available options for hair regrowth. By understanding the biology behind hair growth, and the factors that contribute to hair loss, individuals can evaluate potential treatments and select those that best suit their needs. Notably, Huberman Lab has no affiliation with or financial benefit from any of the products listed, they are provided solely as a useful reference.
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See Original Source
Source Description
In this episode, I explain the biology of hair, hair growth, why hair growth slows and what causes hair to stop growing and/or “fall out.” I discuss the essential role of hair stem cells and other supporting biological factors for healthy hair growth. Then I describe various approaches (mechanical and chemical) to slow hair loss by increasing blood flow to hair stem cells, including minoxidil, tadalafil, PRP, microneedling, Botox and ketoconazole treatments. I also discuss how age-related hormone changes cause hair loss and explain the effectiveness of treatments such as caffeine, saw palmetto, growth hormone, finasteride and dutasteride. For all hair growth options, I describe potential side effects, how soon to expect results and the amount of hair regrowth to expect and I highlight effective combination treatments for hair regrowth even in hair “dead” (bald) zones. For many listeners, thinning, brittle hair, or pattern baldness are a source of anxiety and stress. This episode explains the mechanisms underlying hair regrowth tools and the science behind them so that you can evaluate potential treatments and associated side-effect profiles and select the best one(s) for you.
#HubermanLab #Science #HairGrowth
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
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HVMN: https://hvmn.com/huberman
ROKA: https://roka.com/huberman
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Articles
Microneedling and Its Use in Hair Loss Disorders: A Systematic Review: https://link.springer.com/article/10.1007/s13555-021-00653-2
Caffeine and Its Pharmacological Benefits in the Management of Androgenetic Alopecia: A Review: https://www.karger.com/Article/Fulltext/508228
The effectiveness of combination therapies for androgenetic alopecia: A systematic review and meta-analysis: https://onlinelibrary.wiley.com/doi/10.1111/dth.13741
Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor‐β2/insulin‐like growth factor‐1‐mediated regulation of the hair cycle in male and female human hair follicles in vitro: https://academic.oup.com/bjd/article-abstract/171/5/1031/6616284?redirectedFrom=fulltext&login=false
The structure of people’s hair: https://peerj.com/articles/619/
Note: The Huberman Lab podcast has no affiliation with or financial benefit from any of the products listed below, which are provided as a useful reference only.
Ketoconazole Shampoos
Keeps: https://www.keeps.com/our-products/ketoconazole
Nurx: https://www.nurx.com/topical/ketoconazole-2-shampoo/fb/
Siena Health: https://www.sienahealth.com/product/ketoconazole-shampoo-2
Biotin Shampoos
Maple Holisitics: https://www.amazon.com/Biotin-Hair-Shampoo-Thinning-Moisturizing/dp/B01ENCBOA0
Ouai: https://theouai.com/collections/shampoo-conditioner/products/fine-hair-shampoo
R+Co: https://www.randco.com/collections/dallas-collection/products/dallas-biotin-thickening-shampoo
Microneedling https://www.amazon.com/s?k=microneedling+hair+2mm&crid=OOD2YAB5CQXN&sprefix=microneedling+hair+2mm%2Caps%2C168&ref=nb_sb_noss
Timestamps
00:00:00 Hair
00:04:13 Sponsors: Helix Sleep, HVMN, ROKA
00:08:04 Psychological States & Hair
00:13:19 Hair Anatomy & Stem Cells
00:26:05 3 Phases of Hair Growth
00:35:40 Sponsor: AG1 (Athletic Greens)
00:36:55 Minoxidil & Blood Flow
00:45:37 Increase Blood Flow: Massage, Tadalafil, Platelet-Rich Plasma (PRP), Microneedling
00:56:10 Microneedling, Minoxidil & “Dead Zones”
01:00:13 Sponsor: LMNT
01:01:25 Botox Treatments
01:06:27 Androgens, Hair Growth & Pattern Hair Loss; Scalp vs. Beard Hair
01:15:46 Topical Caffeine & Slowing Hair Loss
01:21:06 IGF-1: Growth Hormone & Sermorelin; Insulin Sensitivity: Myo-Inositol
01:25:52 Iron & Hair Growth
01:27:04 5-Alpha Reductase & Saw Palmetto; Curcumin
01:33:22 Ketoconazole & Offsetting Hair Loss
01:38:46 Topical & Oral Finasteride
01:51:00 Post- Finasteride Syndrome
01:56:01 Dutasteride
01:58:53 Mechanical & Chemical Stimulation for Hair Growth
02:02:46 Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac – https://www.blabacphoto.com
Disclaimer: https://hubermanlab.com/disclaimer
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