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Summary of Transcript:
The video discusses the impact of fasting on the gut microbiome and how different microbes respond to a lack of food. The speakers also talk about the potential for using probiotics to test and measure the effects of breaking a fast in different ways. They highlight the need for more research in this area, but suggest that consumer measurement devices and sequencing companies can play a key role in facilitating personalized medicine in the future. The video also includes a plug for a new book on fasting.
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Summary of Description:
Controlling blood sugar levels is crucial for longevity, according to microbiome company Pendulum Therapeutics CEO Colleen Cutcliffe. She explains to Bulletproof Radio how the microbiome is a crucial aspect of human health, influencing metabolism, digestion, immunity and more. Pendulum Therapeutics combines computer modelling and biological insights to identify and isolate bacterial strains for unique probiotics that have been clinically tested. The company’s work has resulted in the world’s first microbiome intervention for people with type-2 diabetes. Cutcliffe believes the importance of supporting the microbiome will eventually change the way diseases are treated.
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Controlling Blood Sugar: A Key to Longevity
Blood sugar control should be a top priority for anyone aiming to live a long and healthy life. In a recent episode of Bulletproof Radio, Colleen Cutcliffe, Ph.D. – CEO and co-founder of Pendulum Therapeutics – discusses the company’s revolutionary approach to the microbiome and probiotics.
Rather than focusing on disease symptoms, Pendulum examines the microbiome as a bodily infrastructure. The company aims to develop microbiome solutions for various health conditions by identifying and isolating new bacterial strains and combining them to create unique probiotics. Pendulum’s goal is to disrupt the current understanding of probiotics.
Pendulum developed the world’s first microbiome intervention for Type 2 Diabetes, which the company discovered is at the core of numerous health complications. Managed blood sugar is crucial for a healthy immune system, and Pendulum offers free A1c testing at baseline and three months in, so people can track their results.
Pendulum’s clinical trials yielded surprising results. Participants with different stages of diabetes and pre-diabetes achieved positive results, with Type 2 diabetes patients on multiple drugs achieving the most effective results. Pendulum is confident that their approach will help people understand the microbiome as a foundational element in immune responses, digestion, metabolism, and more.
The gut microbiome is a new frontier in defining human health, and the scientific community is learning at an unprecedented pace. Colleen Cutcliffe asserts that microbiome solutions can help to tackle different health conditions as they arise, and that the right flora and plants in your garden can help you maintain better health.
In conclusion, managing what you eat and how you nurture your gut microbiome is a crucial factor in maintaining optimal health, especially in preventing debilitating diseases like Type 2 diabetes. Pendulum Therapeutics is at the forefront of this scientific revolution, developing unique probiotics to help people live their best lives.
Connect with Dave Asprey for more information on how to optimize your health and wellbeing. Check out his new book, “Fast This Way” to learn how to burn fat, combat inflammation, and live like a high-performing human. Follow him on Instagram, Facebook, and Twitter for regular updates, and check out his podcast and blog for informative insights on health, wellness, and productivity.
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Source Description
If you want to do one thing to really live a long time, put controlling your blood sugar high on your list of health goals.
In this episode of Bulletproof Radio, my guest is Colleen Cutcliffe, Ph.D., CEO and co-founder of Pendulum Therapeutics. We explore exciting new discoveries in the body’s gut microbiome and discuss how Pendulum is disrupting what we know about probiotics.
Pendulum uses biological and computational insights into the microbiome to develop solutions for health and disease conditions.
“Rather than calling a disease by what the symptoms are, we are actually looking at the microbiome as an underlying infrastructure within our body,” Colleen says.
Pendulum also identifies and isolates new bacterial strains, then combines those new strains to create unique probiotics. These are backed by clinical research studies. Using this discovery platform, Pendulum created the world’s first microbiome intervention for people with Type 2 Diabetes.
“Managing your blood sugar is at the core of so many health issues, including your immune system,” Colleen says. “You really are more vulnerable and susceptible when you’re not managing your blood sugars properly.”
In Pendulum’s clinical testing, they found out some interesting things.
“We have people with type 2 diabetes on multiple drugs,” Colleen says. “We have people with pre-diabetes who are looking to avoid crossing over into taking drugs. And we’ve had people who are healthy that are really concerned about “how is my body metabolizing sugar and fibers.” And so we offer free A1c testing, actually at baseline, and then three months in so that people can see their results. And I think that really helps people kind of believe the results that they’re experiencing.”
Our conversation goes in a lot of directions related to the science of gut health–both your inner environment and the one around you. We’re learning so much, so fast, that science is seeing all sorts of connections. The gut microbiome is the frontier of how we’ll define better health.
“Where we’re heading is understanding that the microbiome is foundational in a lot of things like the immune response, allergies, digestion, metabolism, and that once you start to make sure that you have the right flora and all the right plants in your garden, you’re actually going to be tackling a lot of these different things,” Colleen says. “And so, you won’t have to have a specific thing for every disease because I think we’re going to transform the way we think about disease.”
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